Pressure Controlled Ventilation – Fundamentals Part 2: Mean Airway Pressure

In the previous tutorial I introduced some of the fundamental elements of pressure control ventilation – time cycling, decelerating flow, pressure ramps etc. This time I discuss, in detail, the concept of mean airway pressure (Pmaw) and describe why increasing Pmaw is an effective way of treating patients with extensive lung disease. In volume controlled ventilation this can be achieved by titrating PEEP upwards and increasing respiratory rate. Care must be taken to keep the plateau pressure below 30cmH2O in the majority of patients. In pressure control Pmaw is generally increased by increasing inspiratory time – extreme care must be taken, though, to avoid escalating Auto-PEEP as this corrodes tidal volume and actually reduces Pmaw.

If auto-PEEP is unavoidable, as it is with inverse ratio ventilation, then extrinsic PEEP should be reduced to ensure that tidal ventilation is maintained. Pmaw can be achieved in volume control by adding an inspiratory pause, and in pressure control by increasing respiratory rate – but these are less effective approaches – in volume control because of necessary flow limitation and in pressure control because of fixed inspiratory times, and Auto-PEEP.
I guarantee you’ll learn something.

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Positive End Expiratory Pressure – Phasic Shunting, Auto-PEEP & ARDS

In the previous tutorials I explained how hypoxemia results from low lung volumes, resulting in low functional residual capacity, airway closure and atelectasis. We looked at the mechanisms by which CPAP reduces the work of breathing in obstructed airways and how, following lung recruitment, PEEP maintains FRC.

In this tutorial I elaborate on these themes. I look at the problem of phasic V/Q mismatch (shunt) during expiration and how it may cause dis-correlation between pulse oximeters and blood gasses. PEEP prevents this at the expense of increasing dead space and negatively impacting ventilation. Optimal PEEP should restore lung compliance – compliance is low with low and high lung volumes. Compliance may also appear poor in pressure control when there is clinically significant auto-PEEP: the ventilator cannot distinguish auto-PEEP from driving pressure and lower than expected tidal volumes may result.

I explain the concept of the “Waterfall” effect to overcome Auto-PEEP. Finally, in our first visit to ARDS, I introduce the problem of deciding on optimal PEEP in that setting. I guarantee that you will learn something. @ccmtutorials http://www.ccmtutorials.org

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Tutorial 14 Mechanisms of Hypoxemia Part 2

This tutorial explains ventilation perfusion mismatch. It will provide you with a platform for understanding oxygen therapy – which I introduce towards the end. I also deal with the concept of oxygen induced hypercarbia. I guarantee you will learn something.  

Contents of This Tutorials:

Ventilation-Perfusion Relationships

Gravity and Blood and Gas Distribution Through the Lungs

Gas and Blood Distribution Through Diseased Lungs

Simplistic Ventilation-Perfusion From Dead Space to Shunt

Stale Gas Within Alveoli

Ventilation Perfusion Relationships – Slimy, Soggy and Stick Alveolar Units

Supplemental Oxygen Therapy For Bronchopneumonia

“Targeted Oxygen Therapy”

When Does Oxygen Therapy Fail? [Shunt]

COPD Flair

Why Does Hyperoxia Cause Hypercarbia (VQ mismatch theory)

The Haldane Effect