Airway Pressure Release Ventilation (APRV)

For the majority of patients admitted to ICU with hypoxic respiratory failure, a conventional ventilatory strategy using volume, pressure or dual control modes with PEEP is usually very effective. With severe lung injury it may be necessary to administer neuromuscular blockade, turn the patient prone and increase the mean airway pressure using PEEP or inverse ratio ventilation (IRV). If these interventions are unavailable, ineffective or inadequate, rescue therapies may be required.

One easily available rescue therapy is Airway Pressure Release Ventilation (APRV). APRV is an extreme version of IRV that looks analogous to using CPAP at high airway pressure levels (e.g. 28cmH2O). Intermittently that high airway pressure is released to remove CO¬ – the release time (less than 1 second) being too short to cause lung derecruitment. Using modern ventilators it is possible utilize the inspiratory capacity to oxygenate the patient (flipping the respiratory cycle from expiration as the primary time of gas exchange to inspiration) and allow the patient to breath spontaneously.

The spontaneous efforts have been shown to improve both gas exchange and cardiovascular performance – but they are not necessary when using this ventilator strategy. Gasping should be avoided. This tutorial covers the science behind APRV, how to set it up, how to use it as part of a ventilator strategy in ARDS, the strengths and limitations of this approach and how to wean it.

I guarantee you will learn something. @ccmtutorials http://www.ccmtutorials.org

Bilevel Pressure Control, BiLevel, BiVent, BiPAP, DuoPAP – a modern mode of ventilation

The introduction of the active expiratory valve was a disruptive technology in critical care mechanical ventilation. This valve flutters when the airway pressure rises above the targeted level – to vent off surplus gas, but maintain airway pressure. It led to the development of newer modes of ventilation (and adjustments to older modes) that allowed the patient to breathe spontaneously independent of the ventilator. As such this was a development of intermittent mandatory ventilation (IMV) – without the risk of breath stacking and expiratory dys-synchrony.

The major mode of ventilation that evolved from the active expiratory valve has several different aliases – BiLevel, BIPAP, BIVENT, DuoPAP etc. but they are all, essentially, pressure controlled intermittent mandatory ventilation modes – that allow the patient to breathe supported or unsupported at a high (Phigh) or low (Plow) airway pressure.

I have chosen the term “Bilevel Pressure Control (BL-PC)” to describe this mode. This tutorial introduces BL-PC, from the perspective of IMV, explains the technology and then discusses the setup and use of the mode. It is a mode of ventilation that is used widely as the “default mode” in many ICUs and can be used in any patient at any time. @ccmtutorials http://www.ccmtutorials.org

Volume Support – The Forgotten Mode?

This tutorial is about Volume Guaranteed Pressure Support – known generally as Volume Support (VS). This, I believe, is an underused mode of ventilation in most ICUs – who prefer to use pressure support. Essentially you specify the desired tidal volume and the ventilator alters to pressure support from breath to breath to deliver something akin to that volume. There is little precision, but – as pressure support is biologically variable anyway – the presence of a volume averaged set of tidal breaths is reassuring, particularly if the bedside practitioner is distracted or inexperienced.
In the tutorial I explain how to set up volume support, what it looks like on three different ventilators – Puritan Bennett, Drager Evita and Servo-i and the strengths and limitations.

Volume Guaranteed Pressure Control (Pressure Regulated Volume Control)

This tutorial is about Volume Guaranteed Pressure Controlled (VG-PC) Ventilation – otherwise known as PC-VG, PRVC, VC+ etc. It is a modern mode of ventilation that aims to deliver a desired tidal volume (volume control) using the pressure controlled paradigm (unlimited flow). As such it is a mode that is often labelled “dual controlled” although, in some ways, it is neither volume controlled, pressure controlled nor both.
Confused? Most are. I have labelled the mode VG-PC – because that is the best approximation – but volume is not necessarily guaranteed and it is certainly not limited. So why bother using this mode. Simply – it works! As a general use “unit default” mode of ventilation VG-PC has few peers: it is nimble enough to be used as the mode of ventilation of choice for patients admitted to ICU following intubation: postoperatively or with respiratory failure.
If the lungs deteriorate – then the mode is versatile enough to deal with it. Being time cycled – mean airway pressure can be easily altered. If compliance or resistance of position changes – then the tidal volume “guarantee” changes the inspiratory pressure from breath to breath to ensure that things remain stable. If the patient breaths spontaneously, using the assist control or SIMV paradigm, flow is increased to meet patient demands. As such it is a very forgiving mode of ventilation, ideal for novices, reassuring to the ICU clinicians. This tutorial explains VG-PC, demonstrates how it is set up in three different ventilators – Puritan Bennetts, Dragers Evitas, Servo I and GE (Aisys) anesthetic machines. I explain the operation of this mode and its strengths and weaknesses. I guarantee you’ll learn something. @ccmtutorials http://www.ccmtutorials.com

Breathe Easy – Automatic Tube Compensation

This tutorial is about Automatic Tube Compensation (ATC). ATC is a setting that has been included in most modern ventilators. Its aim is to reduce the work of breathing associated with the drop in pressure across the endotracheal tube. The ventilator senses pressure, flow and resistance and changes the pressure during the breath to ensure that the patient has the sensation that they are breathing through their own airway. There are two configurations of ATC – one is as an alternative to pressure support in patients who are essentially weaned from mechanical ventilation: essentially a spontaneous breathing trial. The second configuration is as an accessory to all pressure limited modes – such that the pressure waveform is crafted in inspiration and expiration to reduce the workload of breathing during both phases of respiration. @ccmtutorials http://www.ccmtutorials.org